| Property | Address | City | Date Listed |
|---|---|---|---|
| Allen House | 515 1st Ave. W. | Dyersville | 07/10/1975 |
| Andrew-Ryan House | 1375 Locust | Dubuque | 04/11/1985 |
| The Architectural and Historic Resources of Dubuque | Dubuque | 08/12/2004 | |
| Basilica of St. Francis Xavier, Church and Rectory | 114 2nd Street SW | Dyersville | 9/29/1999 |
| Bishop's Block | 90 W. Main Street | Dubuque | 05/19/1994 |
| Carnegie-Stout Public Library | 11th and Bluff Sts. | Dubuque | 08/01/1975 |
| Cathedral Historic District | Roughly bounded by a bluffline running W. of Bluff Street W. 7th Locust and Jones Sts. | Dubuque | 09/25/1985 |
| Diamond Jo Boat Store and Office | Jones and Water Sts. | Dubuque | 11/23/1977 |
| Dubuque Casket Company | 1798 Washington St. | Dubuque | 02/09/2006 |
| Dubuque City Hall | 50 W. 13th Street | Dubuque | 09/14/1972 |
| Dubuque County Courthouse | 720 Central Ave. | Dubuque | 06/23/1971 |
| Dubuque County Jail | 36 E. 8th Street | Dubuque | 06/27/1972 |
| Dubuque Freight House | E. 3rd Street Extension | Dubuque | 10/11/1979 |
| Dubuque Millworking Historic District | White, Jackson, Elm between E. 6th and E. 11th Sts. | Dubuque | 11/07/08 |
| Dubuque Trading Post--Village of Kettle Chief Archeological District | Address Restricted | Dubuque | 11/21/1988 |
| Dubuque Young Men's Christian Association Building | 125 West Ninth Street | Dubuque | 1/31/2002 |
| Epworth School | 310 WEst Main Street | Epworth | 4/21/2004 |
| Four Mounds Estate Historic District | 4900 Peru Road | Dubuque | 1/24/2002 |
| Four Mounds Site | Address Resticted | Dubuque vicinity | 11/17/2000 |
| Fenelon Place Elevator | 512 Fenelon Pl. | Dubuque | 08/03/1978 |
| Garland House | 1090 Langworthy Ave. | Dubuque | 07/07/1983 |
| George W. Rogers Company Shot Tower | Commercial St. and River Front | Dubuque | 5/22/2003 |
| German Bank | 342 Main Street | Dubuque | 03/28/1978 |
| Grand Opera House | 135 8th Street | Dubuque | 9/20/2002 |
| Haberkorn House and Farmstead | W of Sherrill | Sherrill | 01/25/1980 |
| Ham Mathias House | 2241 Lincoln Ave. | Dubuque | 07/19/1976 |
| Hancock Charles T. House | 1105 Grove Terrace | Dubuque | 04/10/1986 |
| Holland Ora House | 1296 Mt. Pleasant Street | Dubuque | 08/14/1986 |
| Hollenfelz House | 1651 White Street | Dubuque | 09/13/1977 |
| Holy Ghost Catholic Historic District | 2887-2921 Central Ave. | Dubuque | 09/15/2011 |
| Interstate Power Company Building | 1000 Main; 131 W. 10th St. | Dubuque | 06/26/2008 |
| Jackson Park Historic District | Roughly bounded by Seventeenth Iowa Tenth and Ninth and Bluff and Montrose Sts. | Dubuque | 07/31/1986 |
| John Bell Block | 1301-1307 Central Avenue | Dubuque | 12/20/2002 |
| Johnson House and Barn | S of Dubuque | Dubuque | 11/05/1974 |
| Julien Dubuque Bridge (Highway Bridges of Iowa MPS) | US 20 over Mississippi River | Dubuque | 8/27/99 |
| Julien Monument | Confluence of Mississippi River and Catfish Creek in Mines of Spain State Recreation Area | Dubuque | 11/21/1988 |
| Kelley House | 274 Southern Ave. | Dubuque | 01/30/1978 |
| Kidder Zephaniah House | 206 1st Ave. NE | Epworth | 11/14/1978 |
| Langworthy Historic District | Langworthy, West Third, Melrose Terrace, between Hill and West 5th, Alpine and Walnut between Solon and West 5th | Dubuque | 08/12/2004 |
| Langworthy House | 1095 W. 3rd Street | Dubuque | 10/14/1975 |
| Lincoln School | About 4 mi. N of Farley | Farley | 07/24/1975 |
| Loetscher T. Ben House | 160 S. Grandview Ave. | Dubuque | 11/02/1989 |
| McMahon House | 800 English Lane | Dubuque | 11/21/1976 |
| Mines of Spain Area Rural Community Archeological District | Address Restricted | Dubuque | 11/21/1988 |
| Mines of Spain Lead Mining Community Archeological District | Address Restricted | Dubuque | 11/21/1988 |
| Mines of Spain Prehistoric District | Address Restricted | Dubuque | 11/21/1988 |
| Old Chapel Hall | 2050 University Ave. | Dubuque | 08/05/1983 |
| Old Main Historic District | Main Street between 1st and 4th Sts. | Dubuque | 01/12/1983 |
| Orpheum Theatre and Site | 405 Main Street | Dubuque | 11/14/1972 |
| The Town Clock Building | 823-25 Main Street | Dubuque | 1/24/2002 |
| Rath Johann Christian Frederick House | 1204 Mt. Loretta Ave. | Dubuque | 04/11/1977 |
| Redstone | 504 Bluff Street | Dubuque | 12/12/1976 |
| Roshek Brothers Department Store | 250 W. 8th St. | Dubuque | 03/17/2010 |
| Round Barn | Dubuque Township 2810 Cascade Rd. | Dubuque | 06/30/1986 |
| Sauser-Lane House | 101 2nd Ave. SW | Cascade | 07/14/1983 |
| Schrup, John and Marie (Palen) Farmstead Historic District | 10086 Lake Eleanor Rd. | Dubuque vicinity | 09/16/2009 |
| Security Building | 800 Main St. | Dubuque | 08/08/2006 |
| Sherrill Mount House | 5259 South Mound Road | Sherrill | 7/11/2002 |
| Shot Tower | Commercial Street and River Front | Dubuque | 11/07/1976 |
| Shroeder-Klein Grocery Company Warehouse | 40-48 Main Street | Dubuque | 02/28/2011 |
| St. Boniface of New Vienna Historic District | 7401 Columbus Street | New Vienna | 9/29/1999 |
| St. Luke's Methodist Episcopal Church | 1199 Main Street | Dubuque | 4/23/1998 |
| Thedinga J. H. House | 340 W. 5th Street | Dubuque | 11/07/1976 |
| Upper Main Street Historic District (Boundary Increase) | 909,951,955,965 Main Street | Dubuque | 02/11/2011 |
| Upper Main Street Historic District | 1000-1100 Main Street | Dubuque | 04/11/2005 |
| Washington Mill Bridge | Creek Branch Lane over Lytle Creek | Bernard vicinity | 6/25/1998 |
| Washington Park | Bounded by 6th 7th Bluff and Locust Sts. | Dubuque | 07/14/1977 |
| Washington Street and East 22nd Street Historic District | 2162-2255 Washington Street and E 22nd Street | Dubuque | 02/28/2011 |
| West 11th Street Historic District | boundry description not available | Dubuque | 08/12/2004 |
| Western Hotel | SE of Holy Cross on U.S. 52 | Holy Cross | 11/07/1976 |
| White Water Creek Bridge | Whitewater Rd. over White Water Creek | Bernard vicinity | 6/25/1998 |
| William M. Black (dredge) | E. 2nd Street | Dubuque | 04/12/1982 |
| Ziepprecht Block | 1347 Central Avenue | Dubuque | 12/20/2002 |